International

Moderna, Merck see positive results from skin cancer vaccine

| By AFP |

The Moderna and Merck drug makers on Tuesday announced positive results from a trial in which messenger RNA technology was used for the first time to make personalized vaccines for skin cancer patients.

The mRNA technology proved vital in the development of vaccines against Covid-19, and scientists have long believed it could help fight other viruses and diseases like cancer.

In a preliminary trial, 150 people who had had their melanoma tumor surgically removed were given up to nine doses of the experimental vaccine alongside the skin cancer treatment Keytruda.

The study showed a 44 percent reduction in risk of death or relapse compared to patients who were only treated with Keytruda, an immunotherapy medicine.

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“Today’s results are highly encouraging for the field of cancer treatment,” Moderna’s Chief Executive Officer Stephane Bancel, said in a statement.

“mRNA has been transformative for COVID-19, and now, for the first time ever, we have demonstrated the potential for mRNA to have an impact on outcomes in a randomized clinical trial in melanoma.”

Moderna and Merck, known as MSD outside of North America, will soon publish the full results of the study, the results of which have not yet been peer-reviewed. The companies will also launch a Phase 3 trial in 2023, which involves a larger number of patients.

Messenger RNA is a molecule within cells that carries instructions to form proteins. Scientists can design them to make a particular protein in the body that can help fight viruses and other illnesses.

Moderna and drugmaker Pfizer-BioNTech were the first to use the technology to create the mRNA vaccines used to fight Covid-19.

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The melanoma vaccine is tailor-made to “prime the immune system so that a patient can generate a tailored antitumor response specific to their tumor mutation signature,” said Moderna’s statement.

Melanoma is the worst form of skin cancer, and nearly 325,000 new cases were diagnosed in 2020. Some 8,000 people are expected to die from melanoma in 2022, said the statement.

Moderna and Merck agreed in October to jointly develop the personalized skin cancer vaccine, for which they will share costs and profits.

Related Topics:Cáncer Merck Moderna Vaccine

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Colombia slams Ecuador’s 30% tariff as ‘economic aggression’

Colombia’s Minister of Mines and Energy, Edwin Palma, on Wednesday described as an “economic aggression” the 30% “security fee” imposed by Ecuadorian President Daniel Noboa on imports from Colombia.

“We reject the tariff measure imposed by Ecuador, an economic aggression that breaks the principle of regional integration,” Palma said in a post on X.

President Noboa explained that the decision was taken due to what he described as a “lack of reciprocity and firm actions” by Colombia in the fight against drug trafficking. He added that despite Ecuador having made “real efforts of cooperation,” including maintaining a trade deficit exceeding $1 billion annually, the country’s armed forces continue to face drug-linked criminal groups along the border without any cooperation.

For that reason, Noboa stated that the measure will remain in place “until there is a real commitment” from Colombia to jointly confront drug trafficking and illegal mining along the 586-kilometer shared border, with the same level of determination Ecuador is currently applying.

According to official data, Ecuador seized 214.5 metric tons of drugs in 2025, down from the record 294.6 tons confiscated in 2024.

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Colombian President Gustavo Petro said on January 7 that during his administration, which began on August 7, 2022 and ends this year, drug seizures have increased significantly, adding that total confiscations are expected to exceed 3,500 tons by the time he leaves office.

International

José Jerí claims destabilization attempt after videos of secretive meetings surface

Peru’s interim president, right-wing leader José Jerí, on Wednesday denounced an alleged plot against him and warned of a deliberate attempt to destabilize the country, following the release of a series of videos showing semi-clandestine meetings with a Chinese businessman, as well as visits to the Government Palace by another businessman of the same nationality who is under house arrest.

“I also want to know who is behind this entire plot. I am an objective and impartial president who does not give in to pressure, but someone has found a way to do so. I want to know who is behind it and what their real objective is,” Jerí said while appearing before Congress’ Oversight and Comptroller Commission.

The interim president, who recently marked 100 days in office after replacing former president Dina Boluarte (2022–2025) in his role as head of Congress, insisted that he has never lied to the country. Without directly accusing any individual or group, he argued that routine activities—such as visiting a restaurant or a shop—are being portrayed with a “malicious” intent.

So far, reports indicate that on December 26, close to midnight, Jerí visited a chifa restaurant—a Peruvian-Chinese eatery—owned by Chinese businessman and state contractor Zhihua “Johnny” Yang, accompanied by Interior Minister Vicente Tiburcio, and wearing a hood. On January 6, he also visited a shop belonging to the same businessman, which had been shut down by municipal authorities just hours earlier.

The revelations have fueled political controversy and renewed scrutiny of the interim administration’s actions amid Peru’s ongoing political instability.

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International

Mexican influencer “La Nicholette” kidnapped in exclusive area of Culiacán

The content creator known as “La Nicholette,” also referred to as “La Muchacha del Salado,” was kidnapped Tuesday afternoon in Isla Musalá, one of the most exclusive residential areas of Culiacán, capital of the northern Mexican state of Sinaloa, according to local media reports on Wednesday.

The abduction was captured by the security camera of the young woman’s vehicle, a lilac-colored Tesla Cybertruck, which was later found abandoned at the scene.

Video footage circulating on social media shows a masked man carrying a long firearm preventing the influencer from entering her vehicle, while another individual forces her into a white sedan, reportedly an older-model Toyota Corolla.

According to media reports, the incident occurred at approximately 5:00 p.m. local time (2300 GMT) at the intersection of Tachichilte Avenue and San Esteban Street, within the Musalá residential area.

Authorities have not yet released official details regarding the victim’s whereabouts or the motives behind the kidnapping.