International
Moderna, Merck see positive results from skin cancer vaccine

| By AFP |
The Moderna and Merck drug makers on Tuesday announced positive results from a trial in which messenger RNA technology was used for the first time to make personalized vaccines for skin cancer patients.
The mRNA technology proved vital in the development of vaccines against Covid-19, and scientists have long believed it could help fight other viruses and diseases like cancer.
In a preliminary trial, 150 people who had had their melanoma tumor surgically removed were given up to nine doses of the experimental vaccine alongside the skin cancer treatment Keytruda.
The study showed a 44 percent reduction in risk of death or relapse compared to patients who were only treated with Keytruda, an immunotherapy medicine.
“Today’s results are highly encouraging for the field of cancer treatment,” Moderna’s Chief Executive Officer Stephane Bancel, said in a statement.
“mRNA has been transformative for COVID-19, and now, for the first time ever, we have demonstrated the potential for mRNA to have an impact on outcomes in a randomized clinical trial in melanoma.”
Moderna and Merck, known as MSD outside of North America, will soon publish the full results of the study, the results of which have not yet been peer-reviewed. The companies will also launch a Phase 3 trial in 2023, which involves a larger number of patients.
Messenger RNA is a molecule within cells that carries instructions to form proteins. Scientists can design them to make a particular protein in the body that can help fight viruses and other illnesses.
Moderna and drugmaker Pfizer-BioNTech were the first to use the technology to create the mRNA vaccines used to fight Covid-19.
The melanoma vaccine is tailor-made to “prime the immune system so that a patient can generate a tailored antitumor response specific to their tumor mutation signature,” said Moderna’s statement.
Melanoma is the worst form of skin cancer, and nearly 325,000 new cases were diagnosed in 2020. Some 8,000 people are expected to die from melanoma in 2022, said the statement.
Moderna and Merck agreed in October to jointly develop the personalized skin cancer vaccine, for which they will share costs and profits.
International
Israel says 136 food aid boxes airdropped into Gaza by six nations

The Israeli military announced on Sunday that 136 boxes of food aid were airdropped into Gaza by the United Arab Emirates, Jordan, Egypt, Germany, and Belgium.
“In recent hours, six countries conducted air drops of 136 aid packages containing food for residents in the southern and northern Gaza Strip,” read the statement, which added that the operation was coordinated by COGAT, the Israeli defense body overseeing civil affairs in the occupied Palestinian territories.
The Israeli military emphasized that they will “continue working to improve the humanitarian response alongside the international community” and reiterated their stance to “refute false allegations of deliberate famine in Gaza.”
The announcement comes as UN agencies warn Gaza faces an imminent risk of famine. More than one in three residents go days without eating, and other nutrition indicators have dropped to their worst levels since the conflict began.
The agencies also noted the difficulty of “collecting reliable data in current conditions, as Gaza’s health systems —already devastated by nearly three years of conflict— are collapsing.”
Meanwhile, Gaza’s Hamas-run Health Ministry reported on Sunday that hospitals in the enclave recorded six deaths from hunger and malnutrition on Saturday, all of them adults.
International
Seven inmates dead, 11 injured after violent riot in Veracruz prison

Seven inmates were killed and eleven others injured in a violent riot and clash inside a penitentiary in the Mexican state of Veracruz, local authorities reported on Sunday.
The disturbance began on Saturday afternoon at the Social Reintegration Center in the port city of Tuxpan, in northern Veracruz, when inmates staged a protest over extortion and assaults allegedly carried out by members of the criminal group known as Grupo Sombra.
The protesting prisoners clashed with another group of inmates and set fires inside and outside the facility, seizing control of the prison for more than 12 hours.
During the takeover, the rioters released several videos, including one showing four prisoners —believed to be members of Grupo Sombra— accusing them of being behind the violence and extortion inside the prison.
It wasn’t until Sunday morning that elements of the Mexican Army, the National Guard, and local police forces managed to enter the prison and regain control. The state’s Public Security Secretariat confirmed that around 9:00 a.m. local time a coordinated operation restored full order and reestablished control of the facility.
Authorities also reported that the fires set by inmates were fully extinguished.
Official figures confirmed the “tragic” deaths of seven inmates and injuries to eleven people, who are now receiving medical treatment in various regional hospitals.
This is the second deadliest riot in Veracruz in the past eight years. In 2018, a violent uprising at the La Toma medium-security prison left seven people dead (six police officers and one unidentified man) and at least 22 injured (15 officers and seven inmates).
The riot follows the kidnapping and killing of retired teacher and taxi driver Irma Hernández, a case that shocked the entire country and was attributed to Grupo Sombra. Images of Hernández kneeling, surrounded by armed men in the municipality of Álamo, sparked nationwide outrage. She was murdered after refusing to pay extortion demands from the criminal organization.
Despite these incidents, Veracruz has not seen a spike in the daily homicide average. In fact, there has been a 1.6% decrease in homicides in the first half of 2025 compared to the same period in 2024, according to the Executive Secretariat of the National Public Security System.
In 2023, the National Institute of Statistics and Geography (INEGI) reported 3,094 incidents in Mexican prisons —an 18.5% increase from the previous year— resulting in 100 deaths and 892 injuries.
International
Study finds COVID-19 vaccines prevented 2.5 million deaths worldwide

COVID-19 vaccines prevented an estimated 2,533,000 deaths worldwide between 2020 and 2024, according to an international study led by Università Cattolica del Sacro Cuore in Italy and Stanford University in the United States, published in the journal JAMA Health Forum. Researchers calculated that one death was prevented for every 5,400 doses administered.
The analysis also found that the vaccines saved 14.8 million years of life, equivalent to one year of life gained for every 900 doses given.
The study, coordinated by Professor Stefania Boccia, revealed that 82% of the lives saved were people vaccinated before becoming infected with the virus, and 57% of deaths avoided occurred during the Omicron wave. In addition, 90% of the beneficiaries were adults over 60 years old.
“This is the most comprehensive analysis to date, based on global data and fewer assumptions about the evolution of the pandemic,” explained Boccia and researcher Angelo Maria Pezzullo.
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