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Novavax starts Covid vaccine trials on children

AFP/Editor

US biotech firm Novavax said Monday it had started clinical trials of its proposed Covid-19 vaccine on children, in a program that will involve up to 3,000 adolescents aged 12-17.

Far fewer children have been sick with Covid-19 compared to adults, and most have mild to no symptoms, but they can be infected and spread the virus.

Novavax said the trials would test “the efficacy (and) safety” of the vaccine, with participants receiving either the vaccine candidate or placebo in two doses, 21 days apart.

Participants will be monitored for up to two years after their injections.

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The Novavax vaccine has not yet been authorized in any country, including for adults, but the company plans to file for emergency authorization in Britain “in the second quarter of 2021”, followed by in the United States.

Novavax announced at the end of January that clinical trials conducted in Britain involving 15,000 adults showed 89.3 percent efficacy.

The Novavax vaccine, which uses different technology from the doses already widely licensed around the world, is a protein-based vaccine engineered from the genetic sequence of the first strain of the coronavirus.

It can be stored at a temperature between 2 and 8 degrees Celsius (35 – 46.4 degrees Fahrenheit).

Other vaccine companies including Moderna, Johnson & Johnson and Pfizer are also conducting trials in adolescents.

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Europe’s medicines watchdog said Monday it had begun evaluating the use of Pfizer/BioNTech’s vaccine for 12- to 15-year-olds, after a similar request in the United States.

Vaccine authorization for children is seen as a crucial step towards achieving herd immunity.

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International

China calls for dialogue amid rising Iran-Israel conflict

The Chinese government emphasized on Monday the importance of “creating the conditions to return to the proper path of dialogue” between Iran and Israel, which have exchanged attacks in recent days resulting in more than 20 Israeli and over 220 Iranian deaths.

Chinese Foreign Ministry spokesperson Guo Jiakun expressed deep concern at a press conference over the Israeli attacks on Iran and the “sudden escalation” of the military conflict.

Guo called on all parties to “take immediate measures to ease tensions and prevent the region from descending into further turmoil,” stating that “force cannot bring lasting peace.”

“If the conflict between Israel and Iran continues to intensify or even expand, the countries of the Middle East will be the first to suffer the consequences,” he added, while noting that China “will continue to maintain communication with the relevant parties, promoting peace and dialogue.”

Chinese Foreign Minister Wang Yi spoke last Saturday with his Iranian and Israeli counterparts to condemn the Israeli airstrike on Iranian territory, which he described as a “violation of international law” with the potential to trigger “disastrous” consequences.

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In both calls, Wang reiterated China’s rejection of the use of force, defended diplomacy as the only solution to the Iranian nuclear dispute, and offered China’s mediation to prevent further destabilization in the Middle East.

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International

Suspect arrested in killing of Minnesota legislator and husband, governor Says

Minnesota Governor Tim Walz announced on Sunday the arrest of Vance Luther Boelter, 57, the main suspect in the killing of Democratic legislator Melissa Hortman and her husband in a Brooklyn Park suburb on Friday night.

Boelter, who also reportedly shot State Senator John Hoffman and his wife early Saturday morning, was apprehended in Sibley County following an intensive manhunt involving hundreds of law enforcement officers.

In a public statement, Governor Walz condemned Boelter’s “unthinkable actions,” which resulted in the death of a woman who “shaped the core of who we are as a state.”

“We cannot become numb to this. We are a deeply divided nation,” Walz said in a statement posted on his X account.

“We move forward not with hatred or violence, but with humility, grace, and civility,” he added.

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Expressing solidarity with the victims’ families, Walz said the entire state of Minnesota is in mourning. He also thanked law enforcement for their bravery and professionalism: “They have saved lives,” he emphasized.

“As we heal, we will not let fear win,” Walz concluded. “We must honor Melissa by moving forward with understanding, service, and above all, humanity.”

Throughout Sunday, police and sheriff units searched a rural area in Minnesota for Vance Luther Boelter, a security company director and preacher who, according to Governor Walz, acted out of politically motivated violence.

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International

40,000 tourists stranded in Israel amid airspace shutdown over Iran conflict

Approximately 40,000 tourists are stranded in Israel following the closure of the country’s airspace amid escalating hostilities with Iran, the Israeli Ministry of Tourism reported on Monday.

The ministry has set up a virtual office to provide information via email (virtual@goisrael.gov.il) and phone (+972-53-583-5808), as well as a Facebook page called Israel Virtual Tourist Office.

Israeli Tourism Minister Haim Katz is in contact with hotels and accommodations across the country to offer support to tourists in need, the ministry added.

Many stranded travelers are considering crossing overland into Jordan or Egypt to seek flights from those countries. The Israel Airports Authority reminded the public that land border crossings remain open.

Three German tourists stranded in Jerusalem told EFE today that they have not received any assistance from their country’s embassy in Israel, and their primary option currently is to cross into Jordan to catch a flight from there.

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Since early Friday morning, Israel launched operations against Iran, targeting military personnel and infrastructure, including energy and nuclear facilities, as well as numerous residential areas in Tehran.

In response, Iran has fired hundreds of ballistic missiles at Israel, some of which have struck various locations across the country, leaving at least 24 dead so far, according to Israeli authorities.

Iranian health officials report at least 224 deaths, mostly civilians, including at least 17 senior military officials—nine from the Revolutionary Guard—and more than a dozen nuclear scientists.

The Israeli military has warned that many more “targets” remain, while Iran’s Revolutionary Guard declared on Monday that it will continue missile attacks against Israel until its “destruction.”

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