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Novavax starts Covid vaccine trials on children

AFP/Editor

US biotech firm Novavax said Monday it had started clinical trials of its proposed Covid-19 vaccine on children, in a program that will involve up to 3,000 adolescents aged 12-17.

Far fewer children have been sick with Covid-19 compared to adults, and most have mild to no symptoms, but they can be infected and spread the virus.

Novavax said the trials would test “the efficacy (and) safety” of the vaccine, with participants receiving either the vaccine candidate or placebo in two doses, 21 days apart.

Participants will be monitored for up to two years after their injections.

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The Novavax vaccine has not yet been authorized in any country, including for adults, but the company plans to file for emergency authorization in Britain “in the second quarter of 2021”, followed by in the United States.

Novavax announced at the end of January that clinical trials conducted in Britain involving 15,000 adults showed 89.3 percent efficacy.

The Novavax vaccine, which uses different technology from the doses already widely licensed around the world, is a protein-based vaccine engineered from the genetic sequence of the first strain of the coronavirus.

It can be stored at a temperature between 2 and 8 degrees Celsius (35 – 46.4 degrees Fahrenheit).

Other vaccine companies including Moderna, Johnson & Johnson and Pfizer are also conducting trials in adolescents.

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Europe’s medicines watchdog said Monday it had begun evaluating the use of Pfizer/BioNTech’s vaccine for 12- to 15-year-olds, after a similar request in the United States.

Vaccine authorization for children is seen as a crucial step towards achieving herd immunity.

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International

Police investigate deaths of Rob Reiner and wife as apparent homicide

The Los Angeles Police Department (LAPD) is investigating the deaths of Hollywood actor and filmmaker Rob Reinerand his wife as an “apparent homicide,” amid a wave of tributes to the director of classics such as When Harry Met Sally.

According to U.S. media reports on Sunday, Rob Reiner and Michele Singer Reiner were found dead at their Los Angeles mansion with what appeared to be stab wounds.

Several political figures shared messages of condolence following the reported deaths of the director of A Few Good Menand his wife.

While the LAPD did not officially confirm the identities of the victims, it stated that homicide detectives were dispatched to the Reiner residence.

“At this time, no additional details are available and the investigation into an apparent homicide is ongoing,” the Los Angeles Police Department said in a statement posted on social media.

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LAPD Deputy Chief Alan Hamilton told reporters that no arrests have been made and that no individuals are currently being questioned as suspects.

“I’m not going to confirm whether anyone is being questioned at this moment or not. We are going to try to speak with as many family members as we can,” Hamilton said.

CNN reported that a family spokesperson confirmed the deaths of Reiner and his wife.

California Governor Gavin Newsom, former U.S. President Barack Obama, and former Vice President Kamala Harrisissued statements expressing their condolences.

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International

U.S. and Mexico Reach Deal to Address Water Deficit Under 1944 Treaty

The United States and Mexico have reached an agreement to comply with current water obligations affecting U.S. farmers and ranchers and for Mexico to cover its water deficit to Texas under the 1944 Water Treaty, the U.S. Department of Agriculture said in a statement.

The department уточified that the agreement applies to both the current cycle and the water deficit from the previous cycle.

On Monday, U.S. President Donald Trump accused Mexico of failing to comply with the water-sharing treaty between the two countries, which requires the United States to deliver 1.85 billion cubic meters of water from the Colorado River, while Mexico must supply 432 million cubic meters from the Rio Grande.

Mexico is behind on its commitments. According to Washington, the country has accumulated a deficit of more than one billion cubic meters of water over the past five years.

“This violation is severely harming our beautiful crops and our livestock in Texas,” Trump wrote on Monday.

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The Department of Agriculture said on Friday that Mexico had agreed to supply 250 million cubic meters of water starting next week and to work toward closing the shortfall.

Agriculture Secretary Brooke Rollins, quoted in the statement, said Mexico delivered more water in a single year than it had over the previous four years combined.

Trump has said that if Mexico continues to fall short of its obligations, the United States reserves the right to impose 5% tariffs on imported Mexican products.

Mexico’s Deputy Foreign Minister for North America, Roberto Velasco, said that a severe drought in 2022 and 2023prevented the country from meeting its commitments.

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International

Several people shot in attack on Brown University campus

Several people were shot on Saturday in an attack on the campus of Brown University, in the northeastern United States, local police reported.

“Shelter in place and avoid the area until further notice,” the Providence Police Department urged in a post on X. Brown University is located in Providence, the capital of the state of Rhode Island.

U.S. President Donald Trump said on his social media platform Truth Social that he had been briefed on the situation and that the FBI was on the scene.

At 5:52 p.m. local time (11:52 p.m. GMT), Brown University said the situation was still “ongoing” and instructed students to remain sheltered until further notice.

After initially stating that the suspect had been taken into custody, Trump later posted a second message clarifying that local police had walked back that information. “The suspect has NOT been apprehended,” the U.S. president said.

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