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Moderna reduces production of COVID-19 vaccine

Moderna reduces production of COVID-19 vaccine

September 13 |

Drugmaker Moderna announced Wednesday that it is scaling back manufacturing of its COVID-19 vaccine, an updated version of which was approved this week by U.S. regulators.

Moderna said the decision is driven by lower post-pandemic demand that will help the company reach its target of 75% to 80% gross revenue growth sooner.

Moderna is in talks with its partners that fill vials and syringes with its messenger RNA-based COVID vaccines globally to reduce production, Stephen Hoge, president of the Massachusetts-based company, said in an interview.

The reduction, Hoge added, will help Moderna adapt to the endemic phase of the disease, which had led to a drop in demand for COVID vaccines as buyers have reduced orders for injections.

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Moderna predicted in August that U.S. demand for the vaccine would reach between 50 million and 100 million doses in the fall season. About 153.8 million COVID injections were administered in the U.S. in 2022, according to the Centers for Disease Control and Prevention.

“For the last two years, we’ve been in pandemic mode producing 1 billion doses a year,” Hoge said. “We’ve been waiting for the time when the pandemic is officially behind us and we need to restructure that manufacturing footprint.”

Following clearance from the U.S. Food and Drug Administration (FDA) on Monday, Moderna said it would begin shipping doses of the COVID vaccine throughout the United States.

The company has agreements to supply its vaccine to other countries, including Britain, Canada and Japan, but does not yet have an agreement with the European Union, according to Hoge, who also said COVID was the focus of Moderna’s manufacturing agreement with China.

Hoge added that while Moderna is urgently working to reduce COVID manufacturing, talks with third-party manufacturers, which will help produce the upcoming respiratory syncytial virus (RSV) and influenza vaccines that investors hope will begin to replace Moderna’s dwindling COVID revenues, could extend into next year.

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“These are relationships we will need for decades to come,” Hoge said.

Moderna also announced Wednesday that it had completed the regulatory filing for its RSV vaccine and that its flu vaccine had generated a stronger immune response against all four A and B strains of the virus compared with traditional flu vaccines in a late-stage trial.

The efficacy of Moderna’s flu vaccine was demonstrated in all age groups, including older patients, and proved to be safe and tolerable, according to the company.

Moderna also said it had found its vaccine to be equal or superior to Sanofi’s high-dose flu vaccine in a separate initial comparative study.

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International

Florida judge sets 2027 trial in Trump’s $10 billion lawsuit against BBC

A federal judge in Florida has scheduled February 2027 for the trial in the lawsuit filed by U.S. President Donald Trump against the BBC, in which he is seeking $10 billion in damages for defamation.

Trump accuses the British broadcaster of airing a misleading edit of a speech he delivered on January 6, 2021, which, he says, made it appear that he explicitly urged his supporters to attack the U.S. Capitol in Washington.

The president filed the suit in December in federal court in Florida, alleging defamation and violations of a law governing business practices when the program was broadcast ahead of the 2024 election.

Trump is seeking $5 billion in damages for each of the two claims.

Lawyers for the BBC unsuccessfully asked the court to dismiss the case, arguing that Trump had not suffered a “legally recognizable harm,” since the investigative program Panorama, which included the edited footage, aired outside the United States.

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Head-of-state diplomacy key to guiding China–U.S. ties, Beijing says

Head-of-state diplomacy plays an irreplaceable strategic guiding role in China–United States relations, Chinese Foreign Ministry spokesperson Lin Jian said on Thursday during a regular press briefing, when asked about high-level exchanges between the two sides.

Lin added that in a recent phone call, U.S. President Donald Trump once again expressed his intention to visit China in April, while Chinese President Xi Jinping reiterated his invitation.

Both sides remain in communication regarding the matter, the spokesperson said.

Lin noted that the essence of China–U.S. economic and trade ties lies in mutual benefit and win-win outcomes.

“Both parties should work together to implement the important consensus reached by the two heads of state, injecting greater certainty and stability into China–U.S. economic and trade cooperation, as well as into the global economy,” he said.

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Trump administration to end special immigration operation in Minnesota

The administration of Donald Trump is bringing to a close its special operation targeting illegal immigration in the northern state of Minnesota, border czar Tom Homan announced Thursday, following weeks of unrest and the fatal shootings of two activists by federal agents.

Thousands of federal officers had been deployed to Minnesota in December to carry out large-scale raids against undocumented immigrants.

The operations triggered strong reactions from residents and advocacy groups, leading to daily confrontations and the deaths of two people who were shot by federal agents.

“I proposed, and President Trump agreed, that this special operation should end in Minnesota,” Homan said during a press conference in the state capital, Minneapolis.

“A significant drawdown began this week and will continue into next week,” he added.

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Homan indicated that similar enforcement efforts could be launched in other cities.

“Next week we will redeploy the agents currently here back to their home stations or to other parts of the country where they are needed. But we will continue to enforce immigration laws,” he said.

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