International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Portuguese Authorities Seize 2.6 Tons of Cocaine Worth More Than $550 Million in Drug Bust
Italian financial police reported Monday that Portuguese authorities intercepted a speedboat carrying more than 2.6 tons of cocaine, with an estimated street value exceeding $550 million.
Four people — two Spanish nationals, one Albanian citizen, and a man from Gibraltar — were arrested in connection with the operation, according to Italian authorities.
The vessel was intercepted off the coast of Lisbon by Portugal’s maritime police following an investigation led by Italian authorities.
Italian financial police estimated that the seized shipment had a street value of approximately 500 million euros ($570 million), making it one of the largest drug seizures reported in the region in recent years.
Portuguese authorities said the interception took place on Thursday, about 90 kilometers (50 nautical miles) southwest of Cape Espichel, during an operation targeting international drug trafficking routes.
International
U.S. and Iran Maintain Ceasefire as Trump Expresses Optimism Over New Talks
U.S. President Donald Trump said Monday that there are “good chances” of reaching an agreement with Iran, as both sides maintained a ceasefire for the third consecutive day following weeks of escalating hostilities.
Trump expressed optimism about the possibility of resuming diplomatic negotiations aimed at ending the conflict, which began in late February and has raised international concerns over its impact on global markets and energy supplies.
The fighting has remained suspended since Saturday, after the United States resumed airstrikes against Iran amid a dispute over control of the Strait of Hormuz, a key route for global oil shipments. The renewed military action had previously caused the collapse of an earlier ceasefire agreement.
Asked about the prospects for negotiations aboard Air Force One, Trump said: “I have a lot of patience… We’ll see what happens. I think there are good chances that something could happen.”
The U.S. president also highlighted Washington’s military capabilities, saying: “We have a lot of ammunition,” while adding that he would like to have more resources due to U.S. support for Ukraine.
U.S. Ambassador to the United Nations Mike Waltz said Trump was allowing diplomatic efforts more time, explaining that the president was “giving some space to the talks” while maintaining that Washington remains prepared to take action if necessary.
Meanwhile, tensions continue in other areas of the Middle East. Saudi Arabia reported that it intercepted drones launched from Iraq by groups allied with Tehran and urged the Iraqi government to take measures to prevent further attacks.
International
Police Investigate After Remains of Five Newborns Found in French Apartment
French authorities have opened a murder investigation after the discovery of human remains believed to belong to five newborn babies inside an apartment in the historic center of a city, the local prosecutor’s office reported Monday night.
According to prosecutors, a 32-year-old woman had given birth at home on Sunday to a healthy baby before being taken to a hospital for medical care.
The discovery was made after the woman’s 32-year-old partner began searching the residence after reportedly learning, once again and at a late stage, that she had been pregnant.
During the search, the man found what appeared to be human remains and informed the hospital, which then alerted prosecutors.
A forensic doctor determined that the remains likely belonged to five newborn infants. Authorities have not yet established the circumstances or motive behind the case.
Investigators have not been able to interview the mother, who remains hospitalized following the delivery.
Prosecutors also confirmed that the couple has two other children, aged eight and nine years old. The investigation remains ongoing as authorities work to clarify the events surrounding the discovery.
Portuguese Authorities Seize 2.6 Tons of Cocaine Worth More Than $550 Million in Drug Bust
U.S. and Iran Maintain Ceasefire as Trump Expresses Optimism Over New Talks
Police Investigate After Remains of Five Newborns Found in French Apartment
Tec de Monterrey honors one of its students for his contribution to nanotechnology in medicine
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