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No preferential nod for Omicron Covid jabs: WHO experts

AFP

There is not yet enough evidence to recommend Omicron-specific Covid-19 jabs over the original versions, the World Health Organization’s vaccine experts said Tuesday.

Four variant-containing mRNA vaccines which include Omicron subvariants BA.1 or BA.4/5 in combination with the ancestral virus have been authorised for use as booster doses.

The vaccines adapted to the globally-dominant variant may offer only a “minute incremental benefit”, the WHO’s Strategic Advisory Group of Experts on Immunisation (SAGE) said.

The WHO has given its Emergency Use Listing green light to nine Covid-19 vaccines and variations — Pfizer/BioNTech, AstraZeneca, Janssen, Moderna, Sinovac, Sinopharm, Bharat Biotech, Novavax and CanSinoBIO.

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“Currently available data are not sufficient to support the issuance of any preferential recommendation for bivalent variant-containing vaccine boosters over ancestral-virus-only boosters”, SAGE said in a statement.

SAGE executive secretary Joachim Hombach said the experts had found that the variant-containing vaccines neutralise to the same extent as the ancestral ones, with a “slightly superior neutralisation of the Omicron variant”.

“It’s a relatively modest effect which we can see in the laboratory,” he said.

“What we cannot do is to relate these laboratory measures with an increase in clinical protection,” because such effectiveness data is not yet available.

“Since our recommendations should be really grounded in evidence, we cannot issue a preferential statement for these vaccines,” Hombach said.

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“These vaccines are absolutely fine, but what is much more important” for protection “is that you actually take the vaccine” — whether tweaked for Omicron or not.

“This is what is making the difference,” whether for the first or second booster, Hombach said.

The Omicron variant accounted for 99.9 percent of virus samples collected in the last 30 days that have been sequenced and uploaded to the GISAID global science initiative.

Of these, the BA.5 group of Omicron sub-variants remain globally dominant at 81 percent, followed by BA.4 at eight percent and BA.2 at three percent.

As of October 2, more than 615 million confirmed Covid-19 cases and over 6.5 million deaths have been reported globally to the WHO.

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  • A syringe is filled with a first dose of the Pfizer Covid-19 vaccine at a mobile vaccination clinic during a back to school event offering school supplies, Covid-19 vaccinations, face masks, and other resources for children and their families at the Weingart East Los Angeles YMCA in Los Angeles, California on August 7, 2021. (Photo by Patrick T. FALLON / AFP) (Photo by PATRICK T. FALLON/AFP via Getty Images)

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International

U.S. warns China over Taiwan during high-level defense talks in Kuala Lumpur

U.S. Secretary of Defense Pete Hegseth expressed concerns over China’s growing military activity near Taiwan during a meeting on Friday with Chinese Defense Minister Dong Jun in Kuala Lumpur.

“It was a constructive and positive meeting,” Hegseth wrote on X. “I emphasized the importance of maintaining a balance of power in the Indo-Pacific and raised U.S. concerns about China’s actions around Taiwan,” the self-governed island that Beijing claims and does not rule out invading.

The meeting took place on the sidelines of the ASEAN Defense Ministers Meeting-Plus, one day after U.S. President Donald Trump met Chinese President Xi Jinping in Busan, South Korea. According to Trump, Taiwan was not discussed during their talks.

“The United States does not seek conflict and will continue to firmly defend its interests, ensuring it maintains the capability to do so in the region,” Hegseth added in his message.

Friday’s encounter followed a September 9 video call between Hegseth and Dong. Their previously planned meeting at the Shangri-La Dialogue in Singapore was canceled due to Dong’s absence from the event.

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Trump’s sit-down with Xi — their first since 2019 — resulted in some trade agreements but avoided addressing the issue of Taiwan, a long-standing source of tension between the world’s two largest powers.

Trump has taken a more ambiguous stance on Taiwan’s future compared with former President Joe Biden, who repeatedly stated that Washington would support Taipei if China launched an invasion. The Republican president has also criticized Taiwan for “stealing” the U.S. semiconductor industry.

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International

U.S. considering airstrikes on military sites in Venezuela, reports say

The United States may soon carry out airstrikes on military facilities inside Venezuela as part of an escalating offensive against Nicolás Maduro’s regime, according to reports Friday from the Miami Herald and The Wall Street Journal, citing sources close to the Trump administration.

Airstrikes could take place “within days or even hours,” the Herald reported. The Journal noted that while the option is under serious consideration, President Donald Trump has not yet made a final decision on authorizing strikes on Venezuelan soil.

Potential targets allegedly include military-controlled ports and airports used in drug trafficking operations, such as naval installations and airstrips, officials told the Journal.

The Herald also quoted a source saying that “Maduro’s time is running out”, suggesting that more than one Venezuelan general may be ready to detain and hand him over. However, officials declined to confirm whether the Venezuelan leader would be among the military targets.

Trump has repeatedly vowed to block the flow of illegal drugs into the United States, following nearly two months of airstrikes against vessels in the Pacific and the Caribbean. Those operations have destroyed 15 boats and left 61 people dead and three survivors since September 1.

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“We are finally waging a war against the cartels — a war like they’ve never seen before — and we are going to win that battle. We are already winning at sea,” Trump told U.S. troops during a speech in Japan.

The reports on possible airstrikes come on the same day the United Nations accused the U.S. of violating international law with its maritime operations, saying those killed at sea may have been victims of extrajudicial executions.

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International

Pope Leo XIV revives Global Compact on Education to confront cultural crisis

Pope Leo XIV announced on Friday that he will revive and update the Global Compact on Education, an initiative launched by the late Pope Francis aimed at deeply transforming global culture through education.

The announcement was made during an audience in St. Peter’s Square, held on the occasion of the Jubilee of the Educational World, which this week gathers more than 20,000 participants from 124 countries in Rome.

During his address, the pontiff — who is of U.S. origin and Peruvian nationality — emphasized the importance of restoring the value of educators and reinforcing the principles that support the pact.

“We must be careful: damaging the social and cultural role of educators means mortgaging our own future,” he warned before thousands in attendance. “A crisis in the transmission of knowledge leads to a crisis of hope.”

The Global Compact on Education, launched by Pope Francis, seeks an integral and long-term cultural transformation. It is structured around five pillars: dignity and human rights; fraternity and cooperation; technology and integral ecology; education for peace and citizenship; and culture and religions. To date, the initiative has been joined by over 553 schools and nearly 410,000 students, according to Catholic Schools data.

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Pope Leo XIV also expressed concern over the widespread inner fragility affecting both students and teachers — many of whom feel overwhelmed by bureaucratic burdens.

He additionally addressed the role of artificial intelligence in education, warning that it may worsen emotional isolation among learners: “It can further isolate students who are already isolated, giving them the illusion that they do not need others — or worse, the feeling that they are unworthy of them,” he said.

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