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No preferential nod for Omicron Covid jabs: WHO experts

AFP

There is not yet enough evidence to recommend Omicron-specific Covid-19 jabs over the original versions, the World Health Organization’s vaccine experts said Tuesday.

Four variant-containing mRNA vaccines which include Omicron subvariants BA.1 or BA.4/5 in combination with the ancestral virus have been authorised for use as booster doses.

The vaccines adapted to the globally-dominant variant may offer only a “minute incremental benefit”, the WHO’s Strategic Advisory Group of Experts on Immunisation (SAGE) said.

The WHO has given its Emergency Use Listing green light to nine Covid-19 vaccines and variations — Pfizer/BioNTech, AstraZeneca, Janssen, Moderna, Sinovac, Sinopharm, Bharat Biotech, Novavax and CanSinoBIO.

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“Currently available data are not sufficient to support the issuance of any preferential recommendation for bivalent variant-containing vaccine boosters over ancestral-virus-only boosters”, SAGE said in a statement.

SAGE executive secretary Joachim Hombach said the experts had found that the variant-containing vaccines neutralise to the same extent as the ancestral ones, with a “slightly superior neutralisation of the Omicron variant”.

“It’s a relatively modest effect which we can see in the laboratory,” he said.

“What we cannot do is to relate these laboratory measures with an increase in clinical protection,” because such effectiveness data is not yet available.

“Since our recommendations should be really grounded in evidence, we cannot issue a preferential statement for these vaccines,” Hombach said.

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“These vaccines are absolutely fine, but what is much more important” for protection “is that you actually take the vaccine” — whether tweaked for Omicron or not.

“This is what is making the difference,” whether for the first or second booster, Hombach said.

The Omicron variant accounted for 99.9 percent of virus samples collected in the last 30 days that have been sequenced and uploaded to the GISAID global science initiative.

Of these, the BA.5 group of Omicron sub-variants remain globally dominant at 81 percent, followed by BA.4 at eight percent and BA.2 at three percent.

As of October 2, more than 615 million confirmed Covid-19 cases and over 6.5 million deaths have been reported globally to the WHO.

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  • A syringe is filled with a first dose of the Pfizer Covid-19 vaccine at a mobile vaccination clinic during a back to school event offering school supplies, Covid-19 vaccinations, face masks, and other resources for children and their families at the Weingart East Los Angeles YMCA in Los Angeles, California on August 7, 2021. (Photo by Patrick T. FALLON / AFP) (Photo by PATRICK T. FALLON/AFP via Getty Images)

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International

Trump: U.S. has hit three venezuelan narco boats in Caribbean

U.S. President Donald Trump said Tuesday that American forces have struck three suspected Venezuelan drug-trafficking vessels in the Caribbean so far, not two as previously reported.

“We took down boats. It was actually three boats, not two, but you only saw two,” Trump told reporters at the White House before departing for a state visit to the United Kingdom.

The president was asked about remarks by Venezuelan leader Nicolás Maduro, who accused Washington of plotting to invade his country.

“Stop sending members of the Tren de Aragua to the United States. Stop sending drugs to the United States,” Trump responded.

The Republican leader mentioned this third vessel a day after announcing that U.S. forces had struck a speedboat in which, according to him, three “terrorists” were killed. Later, from the Oval Office, he claimed the boat had been carrying cocaine and fentanyl.

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The attacks come amid escalating tensions between Washington and Caracas, as the U.S. military maintains a Caribbean deployment under the banner of counter-narcotics operations.

The Trump administration accuses Maduro of heading the so-called Cartel of the Suns, which the Venezuelan government denies. Washington has also offered a $50 million reward for information leading to Maduro’s capture.

On Monday, Maduro said communications with the U.S. were “broken” in the face of what he called an “aggression” and declared that Venezuela is now “better prepared” in case of an “armed struggle.”

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International

Ecuador’s Noboa declares State of Emergency in seven provinces amid fuel price protests

Ecuadorian President Daniel Noboa declared a state of emergency on Tuesday in seven provinces due to what he described as “serious internal unrest,” as road blockades and demonstrations erupted in response to the elimination of the diesel subsidy and growing concerns over insecurity.

The 60-day measure applies to the provinces of Carchi, Imbabura, Pichincha, Azuay, Bolívar, Cotopaxi, and Santo Domingo de los Tsáchilas.

Since Monday, partial protests have been reported in Pichincha, Carchi, Azuay, and Imbabura. On Tuesday, road blockades extended to northern Pichincha and routes in Carchi, near the Colombian border. In response, the Executive headquarters was temporarily relocated to Cotopaxi and the Vice Presidency to Imbabura.

The presidential decree states that the measure comes amid “strikes that have disrupted public order and provoked acts of violence, endangering the safety of citizens and their rights to free movement, work, and economic activity.”

According to the decree, the goal is to “prevent the radicalization of disruptive actions” in the affected provinces and to limit the impact on the population. It further emphasizes that the situation requires an “exceptional intervention by state institutions to safeguard security, guarantee citizens’ rights, maintain public order, and preserve social peace.”

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Social organizations and labor groups, including the Confederation of Indigenous Nationalities of Ecuador (Conaie), have strongly rejected the diesel price increase following the subsidy’s elimination.

The decree justifies the two-month duration as necessary “to ensure a strengthened state presence in the affected territories, restore order, and prevent further acts of violence against people, public, and private property.”

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International

Colombia’s special peace tribunal hands down first sentence against former FARC leaders

Seven former rebel leaders, including their last known commander Rodrigo Londoño, alias “Timochenko,” have been handed the maximum penalty established in the 2016 peace agreement.

Under the ruling, they will face mobility restrictions and be required to carry out activities aimed at restoring the dignity of victims, such as helping locate missing persons and participating in landmine clearance in territories where they once operated. These alternative sentences to prison were part of the historic deal signed in 2016 between the Revolutionary Armed Forces of Colombia (FARC) —once the most powerful guerrilla group in Latin America— and then-President Juan Manuel Santos, Nobel Peace Prize laureate.

The Special Jurisdiction for Peace (JEP) found the ex-commanders guilty of being responsible for the kidnapping of 21,396 people before laying down their arms and transitioning into a political party. “Investigations showed that kidnapping became a systematic practice. These crimes not only broke the law but also left open wounds that persist in families, communities, and the daily life of the country,” a magistrate told reporters in Bogotá, in the absence of the former commanders, who had accepted responsibility for their crimes back in 2022.

It took the tribunal more than seven years to deliver its first ruling, amid criticism from opponents of the peace deal who argue it is too lenient on the rebels. The former commanders still face charges for other crimes against humanity, including the recruitment of minors.

During their decades-long conflict, the FARC held hostage soldiers, police officers, businesspeople, and political leaders, including French-Colombian Ingrid Betancourt. Images of emaciated captives chained in jungle camps shocked the world and became symbols of the conflict.

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