International
Gene mutation can slow child growth, puberty: study
AFP
Scientists have identified a gene mutation that affects the brain’s ability to sense a body’s nutrition and can impact childhood growth and delay puberty, a study said Wednesday.
Average human height has increased over time with greater access to food.
By identifying the gene responsible for the brain receptor known as MC3R, scientists may have uncovered one of the reasons behind this trend.
Analysing data from 500,000 participants in the UK Biobank biomedical research database, they identified a few thousand carrying rare natural mutations in the gene responsible for MC3R receptors.
The study published in Nature shows those individuals were on average shorter and hit puberty later than people without the mutation.
“MC3R deficiency is… associated with reduced childhood growth, adult height and lean mass” the study concludes, noting that the effects are greater the more severe the dysfunction.
Previous studies had shown that mutation in genes responsible for brain receptors known as MC4R lead to obesity in humans.
While studies in mice had suggested MC3R played a role in development, it was not clear how this worked in humans.
“Analysis of the MC3R gene should become part of the routine genetic analysis of patients with delayed puberty, short stature,” the study says.
It concludes that medically stimulating MC3R receptors might be a potential treatment for delayed puberty, short stature and a condition associated with chronic illness that affects muscle mass known as sarcopenia.
International
Petro expresses concern over fatal shooting during mass protests in Lima
Colombian President Gustavo Petro voiced his “concern” on Thursday over recent events in Peru, following the death of a protester reportedly shot during a massive demonstration in Lima against the government and Congress.
“I must express my concern over the events in Peru. A young artist has been killed in citizens’ protests,” Petro wrote on X (formerly Twitter).
The Colombian leader also noted that in Peru, “a popularly elected president remains imprisoned without conviction,” referring to Pedro Castillo, who led the country from July 2021 to December 2022 until he was removed by Congress following a failed attempted coup.
“This is a blatant violation of the American Convention on Human Rights,” Petro stated, adding, “I hope Peru seeks social and political dialogue to legitimize its public institutions.”
On Wednesday, Peru experienced widespread protests in several cities, with the largest demonstration in Lima in recent years, driven by citizens’ concerns over corruption and public insecurity.
During the capital’s mobilization, the Ombudsman’s Office confirmed the death of Eduardo Ruiz, 32, and reported clashes that left over 100 injured, including 78 police officers and 24 protesters, as well as ten arrests.
The Attorney General’s Office, investigating Ruiz’s death “in the context of serious human rights violations,” confirmed that the protester was shot.
International
Peru’s interim president José Jerí refuses to resign after protester’s death in Lima
Peru’s interim president, José Jerí, stated Thursday that he has no intention of resigning from the post he assumed last Friday, following the removal of former president Dina Boluarte, despite growing unrest over the death of a protester during massive demonstrations in Lima on Wednesday.
“I will not resign,” Jerí declared outside the Government Palace in Lima, where he returned on foot after making a surprise visit to Congress headquarters alongside Prime Minister Ernesto Álvarez.
Earlier, after leaving the Legislative Palace, the president acknowledged that the country is going through “difficult times” and condemned what he described as “a small group attempting to impose an agenda different from the citizens’ expression of discontent.”
Jerí expressed condolences for the death of Eduardo Ruiz, a 32-year-old man who died during Wednesday’s protest against the government and Congress, amid growing anger over corruption and insecurity.
“We stand in solidarity with his family,” he said, without offering further details about the incident, which has sparked outrage among Peruvians.
The president also described the demonstrations as “a legitimate civic expression” that later turned violent due to “certain groups seeking to provoke chaos by exploiting a peaceful citizen movement.”
“In a state governed by the rule of law, the rights of both demonstrators and security forces must be protected,” Jerí emphasized, adding that “as a result of that situation, this unfortunate death occurred outside the main area where the protest was taking place.”
International
Mexican government prioritizes 191 communities after deadly floods
Mexican President Claudia Sheinbaum confirmed on Wednesday that the death toll from recent rains and floods across several central states has risen to 66, while the federal government has activated air bridges and prioritized assistance in 191 isolated communities.
“Unfortunately, 66 people have died, and 75 remain missing,” the president said during her morning press conference. She added that the official death toll will be updated later in a new report.
As of Tuesday, authorities had reported 64 fatalities. Sheinbaum also announced the creation of a public information center to centralize official data on the deceased, missing persons, damaged homes, and cut-off communities.
According to the president, the number of missing persons has decreased thanks to coordination with state authorities.
“Through calls to phone line 079, 103 people who had been reported missing have now been located,” she explained.
Priority Municipalities
The president noted that the federal government has classified 191 communities as ‘priority’, a designation based mainly on the percentage of homes affected.
Petro expresses concern over fatal shooting during mass protests in Lima
Panama’s president accuses U.S. Embassy official of visa threats amid China tensions
Peru’s interim president José Jerí refuses to resign after protester’s death in Lima
Tec de Monterrey honors one of its students for his contribution to nanotechnology in medicine
Defense Minister commends salvadoran soldier for Central American Cross Country victory
Extension of the state of emergency approved in southern Chile
-
Central America3 days agoGuatemala arrests first escaped gang member after Barrio 18 prison break
-
International3 days agoMexico reports 64 dead, 65 missing after devastating central region floods
-
International3 days agoVenezuela calls for continued global pressure to secure ‘just peace’ for Palestine
-
International3 days agoPope Leo XIV to skip COP30 in Brazil but plans future visit, Lula confirms
-
Central America4 days agoFraijanes II prison in Guatemala reports gradual escape of 18th Street gang inmates
-
International2 days agoSheinbaum: Urgent to restore access to towns cut off by heavy rains
-
International4 days agoHeavy rains leave dozens dead in Hidalgo, Puebla, and Veracruz
-
International2 days agoArmed forces target illegal mines in Northern Ecuador with bombing raids
-
International2 days agoVenezuelan media faces fresh restrictions after reporting on opposition leader’s Nobel win
-
International1 day agoMexican government prioritizes 191 communities after deadly floods
-
International2 days agoCaracas shuts embassy in Oslo without explanation following Machado’s Nobel win
-
International1 day agoNew road and bridge explosions raise alarm amid indigenous protests in Ecuador
-
International13 minutes agoPeru’s interim president José Jerí refuses to resign after protester’s death in Lima
-
Central America17 minutes agoNicaragua grants 2,500-hectare mining concession to chinese firm in protected region
-
Central America7 minutes agoPanama’s president accuses U.S. Embassy official of visa threats amid China tensions
-
International4 minutes agoPetro expresses concern over fatal shooting during mass protests in Lima