International
AstraZeneca hits snag in Covid drug development
AFP/Editor
Pharmaceutical giant AstraZeneca on Tuesday revealed it had hit a setback in trials of a treatment for Covid-19 symptoms.
The drug, made from a combination of two antibodies, failed its main goal to treat symptoms in exposed patients, the company said in a statement.
The treatment has been undergoing phase 3 or final-stage clinical trials to assess its safety and efficacy.
AstraZeneca said that 1,121 unvaccinated adults had been exposed to an infected person as part of the trial.
Treatment AZD7442 reduced the risk of developing symptoms by only 33 percent — which was “not statistically significant”, it added.
The company is nevertheless continuing trials to assess whether the drug can prevent Covid or treat more severe symptoms.
The US government has funded the development of AZD7442 and has agreements to receive 700,000 doses.
Meanwhile, AstraZeneca’s Covid vaccine, which was developed with the University of Oxford, faced fresh safety doubts.
The jab has been suspended in several European countries over reports of rare blood clots.
A top official in the European Medicines Agency was on Sunday reported as having suggested that it might be worth abandoning AstraZeneca’s vaccine if alternatives were available.
But the EMA said the body’s head of vaccine strategy, Marco Cavaleri, had been misrepresented, and that he believed its benefits outweigh its risks.
“The decision on its use in different populations and ages is the prerogative of the EU Member States, based on specific factors such as virus circulation and vaccine availability,” a spokeswoman said.
A study from British health authorities published on Monday found that two doses of AstraZeneca/Oxford or rival Pfizer/BioNTech vaccines stopped the need for in-patient treatment in more than 90 percent of cases of the Delta variant.
The UK government on Monday announced a four-week delay to the full lifting of coronavirus restrictions in England due to a surge in infections caused by Delta, which first appeared in India.
International
Uribe requests freedom amid appeal of historic bribery conviction
Former Colombian President Álvaro Uribe on Monday requested that the Supreme Court restore his freedom while he appeals the historic 12-year house arrest sentence he received for bribery and procedural fraud.
Uribe, the most prominent figure of Colombia’s right wing, was convicted last week by a lower court for attempting to bribe paramilitary members into denying his ties to the violent anti-guerrilla squads.
Since Friday, the 73-year-old has been under house arrest at his residence in Rionegro, about 30 km from Medellín. The judge justified the measure by citing a risk of flight.
However, Uribe’s defense team rejected that argument and formally petitioned the court to immediately lift the detention order, claiming it lacks legal basis.
Uribe, a dominant force in Colombian politics for decades, is now the first former president in the country’s history to be convicted and placed under arrest, found guilty of witness tampering and obstruction of justice to prevent links to paramilitary groups.
He has repeatedly denounced the trial as politically motivated, blaming pressure from the leftist government currently in power.
His political party, Centro Democrático, has called for nationwide protests on August 7 in support of Uribe, who remains popular for his hardline stance against guerrilla groups.
Uribe has until August 13 to submit his written appeal. The case will then move to the Bogotá High Court, which has until October 16 to uphold, overturn, or dismiss the sentence. If the deadline passes without a decision, the case will be archived.
International
U.S. Embassy staff restricted as gunfire erupts near compound in Port-au-Prince
The poorest country in Latin America and the Caribbean is currently engulfed in a deep political crisis and a wave of violence driven by armed groups — a situation that an international security mission led by Kenya is attempting to stabilize.
Due to the worsening security conditions, the U.S. government has suspended all official movements of embassy personnel outside the compound in Port-au-Prince, the U.S. State Department announced Monday in a security alert posted on social media platform X.
“There are intense gunfights in the Tabarre neighborhood, near the U.S. Embassy,” the alert reads, urging the public to avoid the area.
Tabarre is a municipality located near Port-au-Prince International Airport, northeast of the Haitian capital.
According to a July report by the UN High Commissioner for Human Rights, at least 3,141 people were killed in Haitibetween January 1 and June 30 of this year.
International
Israel says 136 food aid boxes airdropped into Gaza by six nations
The Israeli military announced on Sunday that 136 boxes of food aid were airdropped into Gaza by the United Arab Emirates, Jordan, Egypt, Germany, and Belgium.
“In recent hours, six countries conducted air drops of 136 aid packages containing food for residents in the southern and northern Gaza Strip,” read the statement, which added that the operation was coordinated by COGAT, the Israeli defense body overseeing civil affairs in the occupied Palestinian territories.
The Israeli military emphasized that they will “continue working to improve the humanitarian response alongside the international community” and reiterated their stance to “refute false allegations of deliberate famine in Gaza.”
The announcement comes as UN agencies warn Gaza faces an imminent risk of famine. More than one in three residents go days without eating, and other nutrition indicators have dropped to their worst levels since the conflict began.
The agencies also noted the difficulty of “collecting reliable data in current conditions, as Gaza’s health systems —already devastated by nearly three years of conflict— are collapsing.”
Meanwhile, Gaza’s Hamas-run Health Ministry reported on Sunday that hospitals in the enclave recorded six deaths from hunger and malnutrition on Saturday, all of them adults.
Uribe requests freedom amid appeal of historic bribery conviction
U.S. Embassy staff restricted as gunfire erupts near compound in Port-au-Prince
Israel says 136 food aid boxes airdropped into Gaza by six nations
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Uribe requests freedom amid appeal of historic bribery conviction