International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Costa Rica hails appointment of Japan’s first female Prime Minister, Takaichi Sanae
The Government of Costa Rica on Tuesday congratulated Japan on the appointment of Takaichi Sanae as the country’s first female prime minister and reaffirmed its commitment to strengthening bilateral relations in multiple areas.
“The Government of Costa Rica extends its warmest congratulations to the Government and people of Japan on the election of Prime Minister Takaichi Sanae. Costa Rica celebrates this decision, made by the Japanese Parliament, which for the first time places a woman in such a high office,” the Costa Rican Foreign Ministry said in an official statement.
Costa Rica also reiterated its “strong commitment to further strengthening the traditional bonds of friendship and cooperation between both nations,” and to promoting joint initiatives “based on mutual respect, multilateralism, and shared democratic values.”
The statement also conveyed Costa Rica’s “best wishes for success” to Prime Minister Takaichi and expressed its “hopes for the well-being and prosperity of the Japanese people.”
Takaichi officially became Japan’s first female head of government on Tuesday after winning a parliamentary vote to succeed Shigeru Ishiba, who resigned in September following poor electoral results during his little more than a year in office.
International
Colombian court overturns ex-president Uribe’s conviction for witness tampering
Colombia’s judiciary overturned on Tuesday a conviction against former President Álvaro Uribe for witness tamperingin a case linked to his alleged ties with anti-guerrilla paramilitary groups.
The 73-year-old right-wing leader had become in August the first Colombian ex-president to be criminally convictedand sentenced to 12 years of house arrest for bribery and procedural fraud, following a first-instance ruling that his defense immediately appealed.
However, a judge from the Bogotá Superior Court annulled the conviction, ruling that there was insufficient evidenceto incriminate Uribe. The court also deemed the wiretaps used as evidence illegal and pointed to methodological flaws in the original ruling.
Leftist Senator Iván Cepeda, who filed the complaint against Uribe, announced he will file an appeal in cassation before the Supreme Court of Justice. Speaking at a press conference, Cepeda said he received the decision with “calm and respect,” though he disagreed with it.
After a six-hour reading of the verdict, the hearing concluded with Uribe attending virtually.
Uribe, who governed from 2002 to 2010, spent about 20 days under house arrest before being released on a previous court decision—the same court that has now overturned his conviction.
International
Venezuela accuses U.S. of using anti-drug operations as pretext to target Maduro
Venezuelan Defense Minister Vladimir Padrino criticized on Tuesday what he described as the greater lethality of U.S. anti-drug operations in the Caribbean compared to those in the Pacific, where most drug trafficking routes are concentrated.
Venezuela maintains that the real goal of the U.S. military deployment in the region is to oust President Nicolás Maduro, rather than to combat drug trafficking as claimed by the White House.
Since September, the United States has reported seven attacks in the Caribbean against vessels allegedly linked to Venezuelan drug trafficking. President Donald Trump himself has shared videos of airstrikes on speedboats, with at least 32 people killed in these operations.
“The interdictions carried out in the Pacific do not receive the same treatment as those here in the Caribbean Sea,” Padrino said during a state television broadcast. “What is the real purpose behind this U.S. air and naval deployment in the Caribbean? Is it really about drug trafficking?” he asked.
Venezuelan authorities argue that only 5% of the drugs produced in Colombia leave through Venezuelan territorytoward the Caribbean, claiming that most shipments travel through the Pacific on their way to the United States.
The government also reports an increase in domestic anti-drug operations, showcased by state media, involving the destruction of clandestine airstrips and laboratories, and the seizure of boats, vehicles, and weapons, as well as the shooting down of aircraft allegedly used by traffickers.
On Tuesday, Padrino presented a report on several of these operations alongside the military commanders who led them.
Costa Rica hails appointment of Japan’s first female Prime Minister, Takaichi Sanae
Colombian court overturns ex-president Uribe’s conviction for witness tampering
Venezuela accuses U.S. of using anti-drug operations as pretext to target Maduro
Tec de Monterrey honors one of its students for his contribution to nanotechnology in medicine
Defense Minister commends salvadoran soldier for Central American Cross Country victory
Extension of the state of emergency approved in southern Chile
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