International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Mexican authorities bust Meth Lab and seize tons of drugs and chemicals in multiple states
Mexican authorities dismantled a clandestine laboratory containing 2.5 tons of methamphetamine in the southeastern state of Chiapas, seized a warehouse with more than four tons of chemical precursors in Guerrero (south), and intercepted a trailer in Tijuana attempting to cross into the United States with 2.7 tons of drugs.
Omar García Harfuch, head of the Secretariat of Security and Citizen Protection (SSPC), reported on Saturday via social media that agents from the Criminal Investigation Agency of the Attorney General’s Office (FGR), along with representatives from the Defense Secretariat, Navy (Semar), National Guard (GN), and SSPC, disabled the methamphetamine production lab in Chiapas and confiscated 2.5 tons of the drug.
A statement specified that the agents secured 2.5 tons of methamphetamine, barrels containing substances used to manufacture synthetic drugs, a firearm, and four trucks. In another operation in Guerrero, authorities located over four tons of chemical substances.
The discovery took place on a property in the community of Margarita Maza, Juárez, used to store materials for synthetic drug production. Sufficient evidence was collected and presented to a control judge who authorized the intervention of the property.
In Chiapas, authorities also seized more than 300 barrels and containers with chemicals for making synthetic drugs, as well as various metal containers and devices.
International
Maduro gains support from Venezuelan Assembly amid U.S. drug trafficking accusations
The National Assembly of Venezuela expressed its support this Saturday for President Nicolás Maduro, condemning the United States’ increase in the reward offered for his capture as an “act of aggression.”
U.S. Attorney General Pam Bondi announced on Thursday that Washington had doubled the reward to $50 million for Maduro’s capture, labeling him as one of the “world’s largest drug traffickers.”
“We reject the absurd and desperate actions announced by the U.S. Attorney General’s Office, which are clearly illegal and lack any real basis, beyond being a delirious attempt of aggression against the president (…) and against our rebellious and brave people,” said the Assembly leader, Jorge Rodríguez, while reading a letter he said was unanimously approved by the deputies.
“It is precisely President Nicolás Maduro (…) the protector of the strong democracy that shelters us and the leader who firmly upholds the rule of law and justice,” Rodríguez continued. He is also Venezuela’s chief negotiator in talks with Washington.
Bondi accused Maduro of using “terrorist organizations like the Tren de Aragua, the Sinaloa cartel, and the Cartel of the Suns to introduce lethal drugs and violence” into the United States.
“In 25 years of revolution, we have resisted and advanced despite constant imperialist aggressions. They have not succeeded, and will not succeed, with crude sanctions, criminal blockades, or senseless threats in diverting the noble path the Venezuelan people charted in the free elections of July 28, 2024, in which Nicolás Maduro was elected President of the Republic,” the statement read.
The Venezuelan opposition alleges fraud in those elections and claims victory, and as a result, has boycotted the 2025 legislative, regional, and municipal elections.
International
U.S. doubles bounty on Venezuela’s Nicolás Maduro to $50 million
In February, the United States designated eight Latin American criminal organizations as “global terrorist” groups, including Mexico’s Sinaloa Cartel, Venezuela’s Tren de Aragua, and the MS-13 gang. In July, it added the Cartel of the Suns to the list — a group Washington claims is led by Venezuelan President Nicolás Maduro.
Last Thursday, U.S. President Donald Trump’s administration doubled the reward for information leading to Maduro’s arrest, raising it from $25 million to $50 million, U.S. Attorney General Pam Bondi announced on social media platform X.
U.S. Secretary of State Marco Rubio explained that labeling the Cartel of the Suns as a terrorist organization allows for a strategic shift in dealing with the Venezuelan regime, as it is now also considered a direct threat to U.S. national security, according to El Espectador.
In an interview with The World Over on EWTN, Rubio said the designation enables the U.S. to “use intelligence agencies, the Department of Defense, or any other element of American power to go after them.” He stressed this is no longer just a law enforcement matter, but a national security operation.
When asked at the White House whether he believes it is worth sending the military to combat Latin American drug cartels, Trump responded:
“Latin America has many cartels, a lot of drug trafficking, so, you know, we want to protect our country. We have to protect it.”
Mexican authorities bust Meth Lab and seize tons of drugs and chemicals in multiple states
Maduro gains support from Venezuelan Assembly amid U.S. drug trafficking accusations
U.S. doubles bounty on Venezuela’s Nicolás Maduro to $50 million
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