International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Trump replaces Homeland Security Secretary Kristi Noem with Senator Markwayne Mullin
U.S. President Donald Trump announced Thursday the departure of Kristi Noem as Secretary of Homeland Security, one of the key architects of the administration’s policy of deporting undocumented immigrants.
Noem, who has been assigned a new role as a “special envoy” to Latin America, will be replaced starting March 31 by Republican Senator Markwayne Mullin, the president said in a message posted on his social media platform Truth Social.
According to media reports, Trump made the decision after Noem’s recent hearings in Congress, during which she faced tough questions regarding the awarding of a major public contract.
International
Young Woman Will Represent Mexico at 2026 World Cup Opener, Says President Sheinbaum
Mexico’s president, Claudia Sheinbaum, announced Thursday that the young Mexican woman who proves to have the best ball control skills will receive her personal ticket to the opening match of the 2026 FIFA World Cup in Mexico City.
The left-wing leader had previously said she would not attend the tournament’s opening game on June 11 in the Mexican capital and instead planned to give away the ticket number 00001, reserved for her by FIFA.
During her morning press conference, Sheinbaum explained that women between 16 and 25 years old can participate by submitting a video through an official platform.
“What do they have to do? Keep the ball in the air for one minute,” she said, referring to the soccer juggling challenge that will determine the winner.
Among the judges selecting the winner will be Mexican striker Charlyn Corral, the world’s top female scorer who set a ball-control record in 2005, and professional referee Katia Itzel García.
Sheinbaum also revealed that she plans to watch the opening match during a large public gathering with giant screens in the Zócalo, located in the historic center near the presidential palace.
“Very few people will be able to attend the opening. So I will watch it here with the people, and a young woman will represent me and the people of Mexico,” the president said.
Sheinbaum has previously commented on the high cost of World Cup tickets, as well as the difficulty of obtaining them in a metropolitan area with more than 20 million inhabitants.
In the 2026 tournament, jointly hosted by United States, Mexico, and Canada, Mexico will stage 13 matches in Mexico City, Guadalajara, and Monterrey.
The opening match will take place at the legendary Estadio Azteca, which previously hosted World Cup opening ceremonies in 1970 and 1986, occasions when the presidents in attendance were famously booed by the crowd.
International
Claudia Sheinbaum: Operation Against ‘El Mencho’ Was Based on Pending Arrest Warrants
Mexico’s President Claudia Sheinbaum on Wednesday rejected claims that the military operation that resulted in the death of Nemesio Oseguera Cervantes, known as “El Mencho,” leader of the Jalisco New Generation Cartel (CJNG), was carried out under pressure from the United States government.
Sheinbaum explained that the deployment of federal forces was aimed at executing outstanding arrest warrants against Oseguera Cervantes, who was considered one of the most wanted criminals in both Mexico and the United States.
“That was not the objective (to ease pressure from the United States). It is very important, and I want to repeat it. This individual had an arrest warrant, or several,” Sheinbaum said, referring to the operation conducted on February 22.
According to the president, the initial goal was to capture Oseguera Cervantes, but military forces responded after coming under attack during the intervention.
“The operation was to detain him. The problem is that they were attacked — the Secretariat of National Defense — and they responded at that moment,” she said.
The president insisted that the action was not carried out in response to external demands, although she acknowledged intelligence cooperation with the United States.
“It was not done in any way because of pressure from the United States, not at all. Of course, there was intelligence information from the United States that was used specifically,” she concluded.
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