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WHO launches call to speed up genomics tech development

AFP

Countries should step up their work on genomic technologies to combat diseases, and share that technology more quickly with developing nations, a new WHO report argued Tuesday.

Genomics — the study of DNA sequences and gene functions — could make a vast contribution to improving human health, said the World Health Organization’s Science Council.

“Genomic technologies are driving some of the most ground-breaking research happening today,” said WHO chief scientist Soumya Swaminathan.

“The benefits of these tools will not be fully realised unless they are deployed worldwide.”

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The report included a series of recommendations designed to help make that happen.

Genomics is the study of the total or part of the genetic sequence information of organisms and attempts to understand the structure and function of those sequences. 

Its supporters hope it will provide efficient, cost-effective and robust means of preventing, diagnosing and treating major diseases.

– ‘Enormous contribution’ –

The Science Council was set up in April last year to advise WHO chief Tedros Adhanom Ghebreyesus on advances in science and technology that could directly improve global health.

Made up of nine leading scientists and public health experts, it is chaired by Professor Harold Varmus, a 1989 Nobel laureate and a former director of the US National Institutes of Health.

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The council chose to focus on genomics because of its successes in confronting infectious diseases, cancers, and other chronic diseases.

Genomics uses biochemistry, genetics, and molecular biology to understand and use biological information in DNA and RNA, with benefits for medicine and public health.

“Genomics can make enormous contributions to human health, from surveying populations for infectious agents, such as the virus that causes Covid-19, to predicting and treating a wide variety of diseases, such as cancers and developmental disorders,” said Varmus.

Genome sequencing data became the basis of global monitoring of both how the SARS-CoV-2 virus was evolving, and the emergence of new Covid variants. It was also used in the development of vaccines.

– Bringing down costs –

It is not ethically or scientifically justifiable for less well-resourced countries to gain access to such technologies long after wealthy nations do, the council’s report argued.

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It advocated expanded access to genomic technologies — particularly outside the richest countries — by addressing shortfalls in financing, laboratory infrastructure, materials, and highly trained personnel.

The costs of establishing and expanding genomic technologies were declining, said the report — but they could be brought down further.

Tiered pricing, shared intellectual property rights and investing profits from one area into another could all help make genomic technologies more affordable, it argued.

Ministries should collaborate with scientific organisations on using genomics, building technical capacity and pooling resources with others, the report added.

But it also said that oversight and adherence to international standards was critical in promoting the ethical and legal use of information obtained with genomic methods.

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International

Erin brings strong winds and storm surge despite weakening offshore

Hurricane Erin weakened to a Category 2 storm on Tuesday but continues to pose a threat to parts of the U.S. East Coast with potentially dangerous flooding, according to meteorologists.

Although the hurricane’s eye is expected to remain offshore, experts are concerned about Erin’s size, as strong winds extend hundreds of kilometers beyond the storm’s center.

In its 18:00 GMT bulletin, the U.S. National Hurricane Center (NHC) lifted tropical storm warnings for the Bahamasand Turks and Caicos Islands, but kept them in effect for parts of North Carolina.

Erin was located several hundred kilometers southeast of North Carolina and was moving northwestward.

“This means there is a risk of potentially life-threatening flooding of 60 to 120 centimeters above ground level,” said NHC Director Michael Brennan.

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He also warned of the possibility of destructive waves, combined with storm surge, that could cause severe damage to beaches and coastal areas, making roads impassable.

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International

Three U.S. Warships deploy near Venezuela to combat drug trafficking

Three U.S. naval vessels are moving toward the coasts of Venezuela, according to international media reports on Tuesday, after White House spokesperson Karoline Leavitt confirmed that President Donald Trump is ready to combat and curb international drug trafficking.

Reports indicate that the ships will reach Venezuelan waters within the next 36 hours as part of a recent U.S. deployment aimed at countering international narcotics operations.

The announcement coincides with Leavitt’s statement that Trump is prepared to “use the full extent of his power” to halt drug flows into the United States. The naval deployment involves approximately 4,000 military personnel.

“The President has been clear and consistent. He is ready to use every element of U.S. power to prevent drugs from flooding our country and to bring those responsible to justice. The Maduro regime is not the legitimate government of Venezuela—it is a narco-terror cartel,” the spokesperson said during a press conference.

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International

Cuban authorities free salvadoran convicted in 1997 hotel bombing

Salvadoran national Otto René Rodríguez Llerena was released after serving a 30-year prison sentence for his involvement in a terrorist attack at a hotel in Cuba in 1997, the Cuban Ministry of Foreign Affairs reported.

During his trial, Rodríguez Llerena admitted to placing an explosive device at the Meliá Cohiba Hotel under the orders of anti-Castro exile leaders. He was arrested the following year when he returned to Havana with another load of explosives that failed to detonate.

“The Cuban government reiterates its commitment to combating terrorism, respecting human rights, and the need for the international community to hold accountable those who promote such acts,” the statement read.

He was released on August 15 and is the second Salvadoran to complete his sentence. In December of last year, another Salvadoran, Ernesto Cruz León, was released after planting bombs at tourist centers, one of which killed an Italian tourist identified as Fabio Di Celmo.

A third Salvadoran, Francisco Chávez Abarca, also received a 30-year sentence from Cuban courts in 2010 after being extradited from Venezuela through Interpol for actions against Cuba.

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Rodríguez Llerena had requested conditional release in 2016, arguing that his actions had not caused any direct fatalities, but no further information was released about his situation until now.

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