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EU approves first Covid jab for kids aged 5-11

AFP

The EU cleared Pfizer’s Covid-19 vaccine for use in children aged five to 11 on Thursday, the first jab to be approved in a cohort where the virus is rapidly spreading.

Only a small handful of countries had previously given the nod for coronavirus vaccinations in younger children, including the United States, Israel and Canada.

“I’m glad to tell you that Comirnaty from today has received approval for children five to 11 years of age,” said Marco Cavaleri, head of vaccine strategy at the European Medicines Agency (EMA), using the vaccine’s brand name.

“This is based on a different dose in the one used in adults, essentially it’s a much lower dose,” he told an online public meeting.

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The vaccine was already cleared for use in people aged 12 and over in the 27-nation EU.

Children aged five to 11 will be given one third of the dose that older people receive, with two injections, three weeks apart, the EMA said in a statement.

The vaccine was 90.7 percent effective in a study of nearly 2,000 children of that age, it added. 

Side effects were usually “mild or moderate” lasting a few days, and included pain in the injection site, tiredness, headache, muscle pain and chills.

The EMA “therefore concluded that the benefits of Comirnaty in children aged five to 11 outweigh the risks, particularly in those with conditions that increase the risk of severe Covid-19.”

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But the Pfizer jab’s safety in children “will continue to be monitored closely”.

– ‘Rare in children’ –

Health authorities say children make up an increasing proportion of new cases and hospitalisations in Europe, which is back at the centre of the coronavirus pandemic.

Children are also considered key drivers of infections even when they themselves do not come down with symptoms.

In the Netherlands, where the EMA is based, authorities said earlier this week that the largest increase in cases was among children up to the age of 12. 

“We know that severe Covid-19 and death remain quite rare in children, however disease of all severity occurs in all the paediatric ages,” Cavaleri said.

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“Moreover, high transmission results in increased hospitalisation in children of all ages.”

While children with underlying health conditions were more likely to become ill, the majority of children in hospital with Covid were otherwise healthy, said Cavaleri.

They were also at risk of so-called “long Covid” symptoms dragging on for months after infection, and multisystem inflammatory syndrome, he added. 

The EMA is separately reviewing Moderna’s coronavirus vaccine for children aged 6-11 and expects to reach a decision in January.

The regulator has so far approved four vaccines for use for adults in the EU: Pfizer and Moderna, which use messenger RNA technology, and AstraZeneca and Johnson & Johnson, which use viral vector technology.

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International

Iran Reports 201 Dead, 747 Injured After U.S. and Israeli Strikes

The Iranian Red Crescent Society reported Sunday night (local time) that at least 201 people were killed and 747 injured following attacks carried out by Israel and the United States against the Islamic Republic.

A spokesperson for the humanitarian organization said more than 220 rescue teams have been deployed across affected areas and that relief operations are continuing without interruption. The official highlighted the difficulty of treating the large number of wounded and the urgent need for additional resources in impacted provinces.

Out of Iran’s 31 provinces, 24 have reported damage, according to a statement carried by the Isna news agency. This marks the first overall casualty toll released by Iranian state-affiliated media since the launch of the offensive.

Among the dead are 85 schoolgirls from a school in the southern city of Minab, according to the country’s judiciary. “The number of martyrs at the Minab girls’ school has risen to 85,” the local prosecutor’s office said, as quoted by the judiciary’s website, Mizan Online.

Iranian President Masud Pezeshkian described the attack as a “savagery” that “constitutes a new black page in the record of countless crimes committed by the aggressors.”

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Meanwhile, the international community continues to monitor the situation closely amid concerns about possible further reprisals and the broader impact on Middle East stability, energy markets, and global security.

AFP noted that it was unable to independently verify the casualty figures or the circumstances surrounding the events.

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International

Pope Leo XIV Urges End to ‘Spiral of Violence’ in Middle East

Pope Leo XIV on Sunday called for an end to the “spiral of violence” in the Middle East, following military strikes by the United States and Israel against Iran and subsequent retaliatory bombardments in the region.

“Faced with the possibility of a tragedy of enormous proportions, I urge the parties involved to assume their moral responsibility and stop the spiral of violence before it becomes an irreparable abyss,” the pontiff told the crowd gathered in St. Peter’s Square at the Vatican.

Speaking during the Angelus prayer, the U.S.-born pope said stability and peace cannot be achieved through threats or weapons. “Stability and peace are not built with reciprocal threats or with arms that sow destruction, suffering and death, but only through reasonable, sincere and responsible dialogue,” he declared.

The leader of the world’s 1.4 billion Catholics also called for diplomacy to “regain its role” amid escalating tensions.

In addition, the pope urged Afghanistan and Pakistan to urgently resume dialogue after several days of clashes between the two countries.

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International

Security Council to Hold Emergency Meeting on Middle East Crisis

UN Secretary-General António Guterres on Saturday condemned the “military escalation in the Middle East” following attacks by the United States and Israel against Iran and Tehran’s retaliatory strikes, just hours before an urgent meeting of the UN Security Council.

“I call for the immediate cessation of hostilities and de-escalation,” Guterres said in a statement.

The Security Council is scheduled to meet on Saturday at 21:00 GMT (4:00 p.m. in New York) to address “the situation in the Middle East,” the United Nations announced.

The meeting, during which Guterres will deliver remarks, was convened at the request of France, Bahrain, Colombia, Russia and China, according to a diplomatic source.

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