International
AstraZeneca hits snag in Covid drug development
AFP/Editor
Pharmaceutical giant AstraZeneca on Tuesday revealed it had hit a setback in trials of a treatment for Covid-19 symptoms.
The drug, made from a combination of two antibodies, failed its main goal to treat symptoms in exposed patients, the company said in a statement.
The treatment has been undergoing phase 3 or final-stage clinical trials to assess its safety and efficacy.
AstraZeneca said that 1,121 unvaccinated adults had been exposed to an infected person as part of the trial.
Treatment AZD7442 reduced the risk of developing symptoms by only 33 percent — which was “not statistically significant”, it added.
The company is nevertheless continuing trials to assess whether the drug can prevent Covid or treat more severe symptoms.
The US government has funded the development of AZD7442 and has agreements to receive 700,000 doses.
Meanwhile, AstraZeneca’s Covid vaccine, which was developed with the University of Oxford, faced fresh safety doubts.
The jab has been suspended in several European countries over reports of rare blood clots.
A top official in the European Medicines Agency was on Sunday reported as having suggested that it might be worth abandoning AstraZeneca’s vaccine if alternatives were available.
But the EMA said the body’s head of vaccine strategy, Marco Cavaleri, had been misrepresented, and that he believed its benefits outweigh its risks.
“The decision on its use in different populations and ages is the prerogative of the EU Member States, based on specific factors such as virus circulation and vaccine availability,” a spokeswoman said.
A study from British health authorities published on Monday found that two doses of AstraZeneca/Oxford or rival Pfizer/BioNTech vaccines stopped the need for in-patient treatment in more than 90 percent of cases of the Delta variant.
The UK government on Monday announced a four-week delay to the full lifting of coronavirus restrictions in England due to a surge in infections caused by Delta, which first appeared in India.
International
Trump floats Vance-Rubio potential Republican ticket for 2028 election
U.S. President Donald Trump suggested on Monday that Vice President JD Vance and Secretary of State Marco Rubiocould potentially form a Republican presidential ticket for the 2028 elections.
Speaking during a dinner with law enforcement officials as part of National Police Week, Trump publicly praised both officials and said they could make “an ideal team” for the next presidential race.
“Who likes JD Vance? Who likes Marco Rubio?” Trump asked attendees before adding that the pair “sound like a good combination.”
The president highlighted his vice president’s performance in office, stating that their current partnership has been highly effective. “JD is perfect, that has been a perfect formula,” Trump told reporters later.
He further suggested that a Vance-Rubio pairing could represent a strong presidential and vice-presidential ticket, although he stopped short of offering any formal endorsement.
“I think it sounds like a presidential candidate and a vice-presidential candidate,” he said, while clarifying that his remarks should not be interpreted as an official backing of any future campaign.
So far, neither Vance nor Rubio has publicly confirmed any intention to run in the 2028 presidential election.
Rubio previously sought the Republican nomination in 2016 but withdrew after losing the primary race to Trump. Later, in a December 2025 interview with Vanity Fair, he said he would be among the first to support Vance if he decided to run for the White House.
Vance, meanwhile, has recently dismissed speculation of any political rivalry with Rubio amid growing discussion about potential future GOP leadership.
International
Russia Accuses Ukraine of Violating Victory Day Truce
Russia accused Ukraine on Saturday of violating a Victory Day truce that was reportedly agreed with mediation from the United States, claiming that Ukrainian forces carried out attacks on Russian territory as well as on the annexed Crimean peninsula.
Despite the declared ceasefire, the Russian Ministry of Defense said in a statement that Ukrainian forces attacked Russian military positions using attack drones and artillery.
According to the ministry, Ukrainian forces made twelve attempts to advance toward Russian-held positions across several sectors of the front line.
It also alleged that Ukrainian strikes targeted civilian infrastructure in Crimea, several border regions, the Caucasus, and other areas including Moscow and Perm in the Ural region.
The Defense Ministry estimated around 8,900 violations of the ceasefire in total, including more than 7,000 drone attacks and over 1,000 strikes involving tanks, artillery, multiple rocket launch systems, and mortars since the truce came into effect at midnight.
Russia said its forces responded “symmetrically” to what it described as violations by Ukrainian troops.
Earlier, the Kremlin denied claims that Ukraine attempted to sabotage a military parade in Red Square marking the 81st anniversary of the Soviet victory over Nazi Germany in World War II.
“No attempts were made. Everything went well,” Kremlin spokesperson Dmitry Peskov told local media.
International
Trump Says U.S.-Iran Talks Progressing, Signals Possible Deal on Strait of Hormuz
U.S. President Donald Trump said Wednesday that Washington is holding “very good” talks with Iran and stated that there is a strong possibility of reaching an agreement to end the conflict and reopen the Strait of Hormuz.
“We’ve had very good conversations over the last 44 hours, and it’s very possible that we’ll reach an agreement,” Trump said during an event held in the Oval Office at the White House.
The president’s remarks came just hours after he announced a temporary suspension of the military operation aimed at escorting vessels stranded in the Persian Gulf due to Iran’s blockade of the strategic Strait of Hormuz.
Trump explained that the pause in operations is intended to facilitate diplomatic negotiations between both sides and prevent further military escalation in the region.
“We’re in good shape, and right now things are going well. Now we have to achieve what we need to achieve. If we don’t, we’ll have to go much further,” the Republican president warned.
In a post published on his social media platform Truth Social, Trump reiterated that if Iran accepts Washington’s proposed conditions, military operations and the naval blockade affecting the Islamic republic would come to an end.
However, he also issued a new warning to the Iranian government, stating that the United States would respond with attacks “of greater intensity” if Tehran rejects the agreement promoted by the White House.
Panama confirms drug contamination of El Salvador coffee shipment occurred on its territory
Trump floats Vance-Rubio potential Republican ticket for 2028 election
Russia Accuses Ukraine of Violating Victory Day Truce
Tec de Monterrey honors one of its students for his contribution to nanotechnology in medicine
Defense Minister commends salvadoran soldier for Central American Cross Country victory
